Founded in 1950, Addis Ababa University is a non-profit public higher-education institution located in the urban setting of the metropolis of Addis Ababa (population range of 1,000,000-5,000,000 inhabitants). Officially recognized by the Ministry of Education of Ethiopia, Addis Ababa University (AAU) is a very large (uniRank enrollment range: over-45,000 students) coeducational Ethiopian higher education institution.

Established in 1908, Cairo University is a non-profit public higher-education institution located in the urban setting of the large metropolis of Giza (population range of over 5,000,000 inhabitants). Officially recognized by the Ministry of Higher Education of Egypt, Cairo University (CU) is a very large (uniRank enrollment range: over-45,000 students) coeducational Egyptian higher education institution formally affiliated with the Islamic religion.

Founded in 1919, The American University in Cairo is a non-profit private higher-education institution located in the urban setting of the small city of New Cairo (population range of 50,000-249,999 inhabitants), Cairo. Officially recognized by the Middle States Commission on Higher Education, The American University in Cairo (AUC) is a small (uniRank enrollment range: 5,000-5,999 students) coeducational Egyptian higher education institution.

Founded in 1969, École Nationale Supérieure de Statistique et d'Economie Appliquée (National Higher School of Statistics and Economics) is a non-profit public higher-education institution located in the metropolis of Abidjan (population range of 1,000,000-5,000,000 inhabitants). Officially recognized by the Ministère d’Etat, Ministère du Plan et du Développement, Côte d'Ivoire (Ministry of State, Ministry of Planning and Development of the Ivory Coast), École Nationale Supérieure de Statistique et d'Economie Appliquée (ENSEA) is a coeducational Ivorian higher education institution.

Founded in 1992, Université Alassane Ouattara (Alassane Ouattara University) is a non-profit public higher-education institution located in the medium city of Bouaké (population range of 250,000-499,999 inhabitants), Vallee du Bandama. Officially recognized by the Ministère de l'Enseignement Supérieur et de la Recherche Scientifique de Côte d'Ivoire (Ministry of Higher Education and Scientific Research of the Ivory Coast), Université Alassane Ouattara (UAO) is a medium-sized (uniRank enrollment range: 7,000-7,999 students) coeducational Ivorian higher education institution.

Established in 1996, Institut National Polytechnique Félix Houphouët-Boigny (Félix Houphouët-Boigny National Polytechnic Institute) is a non-profit public higher-education institution located in the urban setting of the medium city of Yamoussoukro (population range of 250,000-499,999 inhabitants).

Established in 1958, Université Marien Ngouabi (Marien Ngouabi University) is a non-profit public higher-education institution located in the urban setting of the metropolis of Brazzaville (population range of 1,000,000-5,000,000 inhabitants). Officially recognized by the Ministère de l'enseignement supérieur, République du Congo (Ministry of Higher Education of the Republic of the Congo), Université Marien Ngouabi (UMNG) is a medium-sized (uniRank enrollment range: 9,000-9,999 students) coeducational Congolese higher education institution.

Established in 2011, Université Emi Koussi (Emi Koussi University) is a for-profit private higher-education institution located in the large city of N'djamena (population range of 500,000-1,000,000 inhabitants), Ndjamena. Officially recognized by the Ministère de l'Enseignement Supérieur, de la Recherche Scientifique et de la Formation Professionnelle, Tchad (Ministry of Higher Education, Research and Vocational Training of Chad), Université Emi Koussi (UNEK) is a coeducational Chadian higher education institution.

Founded in 1963, École Nationale d'Administration, Tchad (National School of Administration) is a non-profit public higher-education institution located in the large city of N'Djamena (population range of 500,000-1,000,000 inhabitants), NDjamena. Officially recognized by the Ministère de l'Enseignement Supérieur, de la Recherche Scientifique et de la Formation Professionnelle, Tchad (Ministry of Higher Education, Research and Vocational Training of Chad), École Nationale d'Administration, Tchad (ENA) is a coeducational Chadian higher education institution.

Founded in 1971, Université de N'Djaména (University of N'Djaména) is a non-profit public higher-education institution located in the large city of N'Djamena (population range of 500,000-1,000,000 inhabitants), NDjamena. Officially recognized by the Ministère de l'Enseignement Supérieur, de la Recherche Scientifique et de la Formation Professionnelle, Tchad (Ministry of Higher Education, Research and Vocational Training of Chad), Université de N'Djaména (UNDT) is a coeducational Chadian higher education institution.